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Bernard and Christine Thisse
The Department of Cell Biology and the Morphogenesis and Regenerative Medicine Institute are excited to welcome Christine and Bernard Thisse to the UVA faculty in August, 2007.
Drs. Christine and Bernard Thisse both received PhD degrees from University Louis Pasteur in Strasbourg, France. They initial work was on the function of twist and dorsal genes during early development of Drosophila embryo. They began their career in zebrafish research as post-docs at the University of Oregon and later returned to France to build their own research program at the IGBMC (Institute of Genetic Molecular and Cellular Biology) in Illkirch / Strasbourg . Christine and Bernard have jointly served as Director of Research for the CNRS (National Center for Scientific Research) and group leader in the Department of Developmental Biology at the IGBMC. Christine is a member of the National Committee of the CNRS and Bernard is the current President of the French Society of Developmental Biology.
Their current research is mainly focusing on patterning and signaling at early developmental stages. The goal is to identify the molecular mechanisms responsible for the definition of cell identity and to study the cellular response in both gene expressions and cell behaviors resulting from the initial stimulation by morphogenes.
Seiliez I, Thisse B, Thisse C (2006) FoxA3 and goosecoid promote anterior neural fate through inhibition of Wnt8a activity before the onset of gastrulation. Dev Biol. 290:152-63.
Fürthauer M, Van Celst J, Thisse C, Thisse B (2004)FGF signalling controls the Dorso-Ventral patterning of the zebrafish embryo. Development. 131: 2853-64.
Agathon A., Thisse C, Thisse B (2003) The molecular nature of the zebrafish tail organizer. Nature. 424: 448-52.
Thisse B, Wright C. V. E., Thisse C (2000) Activin and Nodal-related factors control antero-posterior patterning of the zebrafish embryo. Nature 403: 425-27.